The other evening I got off the metro in a strange neighborhood. I knew I had to go south on Georgia Ave, a major-north south route, but wasn't sure which way that was.
But I was in luck - there was a city bus waiting at the corner. So I stopped and asked the driver if I was walking south.
He was all, "Uh..."
I finally got an answer by asking if it was the downtown direction or the Maryland direction, but he even had to think pretty hard about that one.